300+ Mind Expanding Documentaries

mind expanding docs

I watch a lot of documentaries. I think they are incredible tools for learning and increasing our awareness of important issues. The power of an interesting documentary is that it can open our minds to new possibilities and deepen our understanding of the world. On this list of mind expanding documentaries you will find different viewpoints, controversial opinions and even contradictory ideas. Critical thinking is recommended. I’m not a big fan of conspiracy documentaries but I do like films that challenge consensus reality and provoke us to question the everyday ideas, opinions and practices we usually take for granted.

Watching documentaries is one of my favorite methods of self-education. If I find a documentary inspiring, I usually spend more time researching the different ideas and interesting people interviewed in the film.

I hope you find these documentaries as enlightening as I did!

If you notice that a link is broken, please let me know in the comments and I’ll update it.

Thanks to Kyle Pearce & DIY Genius for this awesome list!

[1] Life In The Biosphere

Explore the wonder and interconnectedness of the biosphere through the magic of technology.

1. Home
2. How Many People Can Live on Planet Earth
3. The Magical Forest
4. Ants: Nature’s Secret Power
5. Mt. Everest: How It Was Made
6. Mariana’s Trench: The Deepest Spot On Earth
7. Natural World: The Andes
8. Shining Mountains: The Rockies
9. Grand Canyon: How It Was Made
10. The Intelligence of Plants

[2] Creativity and Design:

Learn about all the amazing things that people create with their imaginations.

1. Everything Is A Remix
2. The Creative Brain: How Insight Works
3. Blow Your Mind
4. Design: The New Business
5. PressPausePlay: Art and Creativity in the Digital Age
6. Infamy: A Graffiti Documentary
7. Influencers: How Trends and Creativity Become Contagious
8. RIP: A Remix Manifesto
9. Design: e² – Sustainable Architecture
10. The Genius Of Design

[3] The Education Industrial Complex:

The modern school where young minds are moulded into standardized citizens by the state.

1. The College Conspiracy
2. Declining by Degrees: Higher Education at Risk
3. The Forbidden Education
4. Default: The Student Loan Documentary
5. College Inc.
6. Education For A Sustainable Future
7. Networked Society: The Future of Learning
8. The Ultimate History Lesson With John Taylor Gatto
9. The Education System in Communist China
10. The War On Kids

[4] The Digital Revolution:

The Internet is now the driving force behind change and innovation in the world.

1. Download: The True Story of the Internet
2. The Age of Big Data
3. Resonance: Beings of Frequency
5. Life In A Day
6. Networked Society: On The Brink
7. Us Now: Social Media and Mass Collaboration
8. WikiRebels: The WikiLeaks Story
9. The Virtual Revolution: The Cost of Free
10. How Hackers Changed the World

[5] A New Civilization:

We are at the dawn of a new golden age of human inventiveness.

1. THRIVE: What On Earth Will It Take?
2. Zeitgeist III: Moving Forward
3. Paradise or Oblivion
4. 2012: Time For Change
5. The Crisis of Civilization
6. The Collective Evolution II
7. The Quickening: Awakening As One
8. 2012 Crossing Over: A New Beginning
9. Collapse
10. The Awakening

[6] Politics:

Explore the politics of power and control and how it affects your life.

1. Owned and Operated
2. UnGrip
3. The Power Principle
4. The True Story of Che Guevara
5. Earth Days
6. Capitalism Is The Crisis
7. WikiLeaks: The Secret Life of a Superpower
8. The Putin System
9. The War On Democracy
10. Rise Like Lions: Occupy Wall Street and the Seeds of Revolution

[7] Biographies of Genius:

The biographies of modern geniuses who pushed humanity forward.

1. Isaac Newton: The Last Magician
2. Nikola Tesla: The Greatest Mind of All Time
3. The Unlimited Energy of Nicola Tesla
4. The Missing Secrets Of Nikola Tesla
5. Richard Feynman: No Ordinary Genius
6. How Albert Einstein’s Brain Worked
7. The Extraordinary Genius of Albert Einstein
8. The Biography of Albert Einstein
9. Da Vinci: Unlocking The Genius
10. Leonardo Da Vinci: The Man Who Wanted to Know Everything

[8] War:

War is history’s oldest racket for stealing from the powerless and redistributing resources to the powerful.

1. Psywar: The Real Battlefield Is Your Mind
2. The History of World War II
3. The Secret History of 9/11
4. Robot Armies in the Future
5. The Never Ending War in Afghanistan
6. Shadow Company: Mercenaries In The Modern World
7. World War II From Space
8. Why We Fight
9. The Fog Of War
10. The Oil Factor: Behind The War On Terror

[9] Economics:

Learn about the financial system works and how people and societies are enslaved through debt.

1. The Corporation: The Pathological Pursuit of Profit and Power
2. Overdose: The Next Financial Crisis
3. The Ascent of Money: A Financial History of The World
4. The One Percent
5. Quants: The Alchemists of Wall Street
6. The Last Days Of Lehman Brothers
7. The Four Horsemen
8. Inside Job: The Biggest Robbery In Human History
9. Capitalism A Love Story
10. Money and Life

[10] Digital Entrepreneurship:

Profiles of the entrepreneurs who used technology to change the world.

1. The Life Of A Young Entrepreneur
2. Profile: Google’s Larry Page and Sergey Brin
3. Profile: Facebook’s Mark Zuckerberg
4. Starting-Up in America
5. The Biography of Bill Gates
6. Inside Google: The Billion Dollar Machine
7. Steve Jobs: One Last Thing
8 . Steve Jobs: The Billion Dollar Hippy
9. Elon Musk: Risk Takers
10. The Story of Twitter

[11] Sports:

Watch the inspiring stories of amazing athletes.

1. Fearless: The Jeb Corliss Story
2. Carts of Darkness
3. The Two Escobars
4. Usain Bolt: The World’s Fastest Man
5. Wayne Gretzky: The Life and Times
6. When We Were Kings
7. Mike Tyson: Beyond the Glory
8. Birdmen
9. The Legacy Of Michael Jordan
10. We Ride: The Story of Snowboarding

[12] Technology:

Find out more about the impact of exponential growth and the approaching Singularity.

1. Ray Kurzweil: The Transcendent Man
2. How Robots Will Change the World
3. Human 2.0
4. Tomorrow’s World: Life In The Future
5. Trance-Formation: The Future of Humanity
6. The Venus Project: Future By Design
7. Bionics, Transhumanism And The End Of Evolution
8. The Singularity Is Near
9. Car Technology Of The Future
10. Powering The Future: The Energy Revolution

[13] Origins of Religion:

Explore the original religious experience of mankind at the dawn of civilization.

1. Entheogen: Awakening the Divine Within
2. Manifesting the Mind: Footprints of the Shaman
3. Ancient Egypt and The Alternative Story of Mankind’s Origins
4. The Hidden Knowledge of the Supernatural
5. Re-Awaken: Open Your Heart, Expand Your Mind
6. Shamans of the Amazon
7. The Root of All Evil: The God Delusion
8. Ancient Knowledge
9. The Naked Truth
10. Before Babel: In Search of the First Language

[14] Western Religion:

The fascinating history of the three Abrahamic religions: Judaism, Christianity and Islam.

1. Secret Quest: The Path of the Christian Gnostics
2. The Secret Gate of Eden
3. Forbidden Knowledge: Lost Secrets of the Bible
4. Banned From The Bible: Secrets Of The Apostles
5.  The Life of Prophet Muhammad
6. The Road To Armageddon
7. The Most Hated Family In America
8. Muhammad: The Legacy of a Prophet
9. A Complete History of God
10. Gnosis: The Untold History of the Bible

[15] Eastern Religion:

Expand your mind by also studying the entirely different religious worldviews of the East.

1. Inner Worlds, Outer Worlds
2. The Life Of The Buddha
3. The Seven Wonders of the Buddhist World
4. Mysteries of the Cosmic OM: Ancient Vedic Science
5. Where Science and Buddhism Meet
6. The Yogis of Tibet
7. Taj Mahal: Secrets To Blow Your Mind
8. Light at the Edge of the World: Tibetan Science of the Mind
9. Myths of Mankind: The Mahabharata
10. Ayurveda: The Art of Being

[16] Consciousness:

Learn about the basic unity of existence and the miracle of consciousness.

1. Athene’s Theory of Everything
2. Theory of Everything: GOD, Devils, Dimensions, Dragons & The Illusion of Reality
3. The God Within: Physics, Cosmology and Consciousness
4. 5 Gateways: The Five Key Expansions of Consciousness
5. Return to the Source: Philosophy and The Matrix
6. The Holographic Universe
7. DMT: The Spirit Molecule
8. What Is Consciousness?
9. Kymatica
10. Neuroplasticity: The Brain That Changes Itself

[17] Mysteries:

Indiana Jones-style explorations into the unsolved mysteries of the past.

1. Alchemy: Sacred Secrets Revealed
2. The Day Before Disclosure
3. The Pyramid Code
4. The Secret Design of the Egyptian Pyramids
5. Decoding the Past: Secrets of the Dollar Bill
6. The Lost Gods of Easter Island
7. Origins of the Da Vinci Code
8. Forbidden Knowledge: Ancient Medical Secrets
9. Secret Mysteries of America’s Beginnings: The New Atlantis
10. Secrets in Plain Sight

[18] Mass Culture:

Learn about how our thoughts and opinions are influenced by mass culture.

1. The Century of the Self
2. All Watched Over By Machines Of Loving Grace
3. The Power Of Nightmares
4. The Trap: What Happened To Our Dreams of Freedom
5. Starsuckers: A Culture Obsessed By Celebrity
6. Human Resources: Social Engineering in the 20th Century
7. Obey: The Death of the Liberal Class
8. Motivational Guru: The Story of Tony Robbins
9. Bob Marley: Freedom Road
10. Radiant City

[19] Corporate Media:

Discover how the mass media and advertisers channel our irrational impulses.

1. Weapons of Mass Deceptions
2. Secrets of the Superbrands
3. Orwell Rolls in his Grave
4. The Esoteric Agenda
5. Propaganda
6. The Myth of the Liberal Media: The Propaganda Model of News
7. Manufacturing Consent: Noam Chomsky and the Media
8. Symbolism in Logos: Subliminal Messages or Ancient Archetypes
9. Edward Snowden: A Truth Unveiled
10. Outfoxed: Rupert Murdoch’s War on Journalism

[20] Art and Literature:

Explore the lives of famous artists and how art opens people’s minds.

1. Lord Of The Rings: Facts Behind The Fiction
2. Cosm: Alex Gray’s Visionary Art
3. Banksy’s Exit Through The Gift Shop
4. New Art and the Young Artists Behind It
5. Salvador Dali: A Master of the Modern Era
6. How Art Made The World: More Human Than Human
7. The Day Pictures Were Born
8. Guns, Germs and Steel
9. Off-Book: Digital Age Creativity
10. This Is Modern Art

[21] Health:

Explore issues in health, how our bodies work and the incredible power of our brains.

1. The Human Brain
2. The Truth About Vitamins
3. How To Live To 101
4. America’s Obesity Epidemic
5. The War On Health
6. The Beautiful Truth
7. Food Inc.
8. The Truth About Food
9. Addicted To Pleasure: Sugar
10. The Living Matrix

[22] Drugs:

Documentaries on the effect of drugs — legal and illegal — on the body and mind.

1. The Union: The Business Behind Getting High
2. The Drugging Of Our Children
3. How Marijuana Affects Your Health
4. Making a Killing: The Untold Story of Psychotropic Drugging
5. Clearing the Smoke: The Science of Cannabis
6. LSD: The Beyond Within
7. The War on Drugs: The Prison Industrial Complex
8. Are Illegal Drugs More Dangerous Than Legal Drugs?
9. The Prescription Drug Abuse Epidemic
10. Run From The Cure: The Rick Simpson Story

[23] Environment:

Thought-provoking documentaries on the environmental movement and the growing threats to our biosphere.

1. Earthlings
2. Blue Gold: World Water Wars
3. Tapped
4. Shift: Beyond the Numbers of the Climate Crisis
5. All Things Are Connected
6. The Fight For Amazonia
7. Flow: For Love Of Water
8. Here Comes the Sun
9. The World According To Monsanto
10. The Story of Stuff

[24] Cosmos:

Expand your mind by exploring our indescribably large and beautiful Cosmos.

1. The Search for Planets Similar to Earth
2. Inside the Milky Way Galaxy
3. Cosmic Journeys : The Largest Black Holes in the Universe
4. Beyond The Big Bang
5. The Mystery of the Milky Way
6. Fractals: The Hidden Dimension
7. Into The Universe With Stephen Hawking: The Story of Everything
8. Pioneer Science: Discovering Deep Space
9. Carl Sagan’s Cosmos
10. The Strangest Things In The Universe

[25] Science:

The history of scientific discovery and how scientific instruments expand our perception.

1. The Complete History of Science
2. The Quantum Revolution
3. Secret Universe: The Hidden Life of the Cell
4. Stephen Hawking: A Brief History of Time
5. Quantum Mechanics: Fabric of the Cosmos
6. The Light Fantastic
7. DNA: The Secret of Life
8. Parallel Universes, Alternative Timelines & Multiverse
9. What Is The Higgs Boson?
10. Infinity

[26] Evolution:

The story of our evolution and the emergence of self-aware human beings.

1. The Origin of Life
2. Homo Sapiens: The Birth of Humanity
3. Beyond Me
4. The Global Brain
5. Metanoia: A New Vision of Nature
6. Birth Of A New Humanity
7. Samsara
8. Ape Man: Adventures in Human Evolution
9. The Incredible Human Journey
10. The Human Family Tree

[27] Psychology and The Brain:

New research is shining a spotlight on how we can improve our brains.

1. How Smart Can We Get?
2. The Science of Lust
3. The Secret You
4. What Are Dreams?
5. A Virus Called Fear
6. Beyond Thought (Awareness Itself)
7. The Human Brain
8. Superconscious Mind: How To Double Your Brain’s Performance
9. How Does Your Memory Work?
10. Secrets of the Mind

[28] Modern History:

The story of the Enlightenment, the Industrial Revolution and the rise of the modern world.

1. The Entrepreneurs Who Built America
2. History of the World in Two Hours
3. The Industrial Revolution
4. The Rise and Fall of the Third Reich
5. The Adventure of the English Language
6. The French Revolution
7. Big Sugar
8. The Spanish Inquisition
9. The American Revolution
10. The Mexican American War

[29] Pre-Modern History:

The story of the Americas and European history in the pre-modern world.

1. America Before Columbus
2. The Dark Ages
3. Socrates, Aristotle and Plato
4. The Medici: The Most Influencial Family In The World
5. Rome: The Rise And Fall Of An Empire
6. History of Britain: The Myth of the Anglo-Saxon Invasion
7.  A History of Celtic Britain
8. The Crusades: Victory and Defeat
9. The Vikings: Voyage To America
10. Copernicus and the Scientific Revolution

[30] Current Events:

Become more informed about current events that are shaping the world.

1. Syria: The Reckoning
2. Empire: Putin’s Russia
3. The New Arms Race
4. The Killing of Yasser Arafat
5. Egypt In Crisis
6. Inside Obama’s Presidency
7. The Untouchables: How Obama Protected Wall Street
8. Behind The Rhetoric: The Real Iran
9. A History of the Middle East since WWII
10. Climate Wars

[31] Ancient Civilizations:

Fascination explorations into the ancient civilizations of our past.

1. When God Was a Girl: When Goddesses Ruled The Heavens and Earth
2. The Persian Empire : Most Mysterious Civilization in the Ancient World
3. What The Ancients Did For Us
4. What the Ancients Knew
5. Egypt: Beyond the Pyramids
6. Secrets of the Ancient Empires
7. Constellations & Ancient Civilizations
8. Graham Hancock’s Quest For The Lost Civilization
9. Atlantis: The Lost Continent
10. Seven Wonders of the Ancient World

I hope you enjoy watching some of these mind expanding documentaries! If you have a personal favorite, please share it with everyone in the comments.

Studies Link DNA Damage from Synthetic Antibiotics To Autism

antibioticsBayer, the maker of the world’s most unsafe brands of birth control – the Yasmin line and the Mirena/Skyla IUDs, as well as a maker of neocontinid pesticides killing the bees – can now be held responsible for the rise in Autism rates over the last 30 years, as they are the makers and manufacturers of Cipro and Avelox, two of the world’s most popular fluoroquinolone antibiotics, which have recently been shown to alter DNA in ways that encourage expression of Autism related genes. Johnson & Johnson, the maker of Levaquin, also a popular fluoroquinolone antibiotic, can also be held responsible for the atrocity of one in eighty-eight children being autistic, as Levaquin is also a fluoroquinolone antibiotic that does the same thing.

Cipro (ciprofloxacin) is a second generation fluoroquinolone patented in 1983 by Bayer, Levaquin (levofloxacin) is a third generation fluroquinolone patented in 1987 by Ortho-McNeil-Janssen (a division of Johnson & Johnson), and Avelox (moxifloxacin) is a fourth generation fluoroquinolone patented in 1991 by Bayer. In the 1980s the incidence of Autism was 1 per 1,000 children, today it is 1 per 88 children. The incidence of Autism has gone up hand in hand with the use of fluoroquinolone antibiotics.

Of course, this correlation between the introduction of fluoroquinolone antibiotics to the market and increasing rates of Autism, proves nothing. For proof, studies, experimentation and scientific exploration are needed. In September, 2013 the studies of topoisomerase inhibitors like fluoroquinolones as they relate to Autism commenced with an article in Nature entitled “Topoisomerases facilitate transcription of long genes linked to autism.”

Fluoroquinolone Antibiotics Lead to Autism Gene Expression

Fluoroquinolone antibiotics are eukaryotic DNA gyrase (also known as topoisomerase II) and topoisomerase IV inhibitors. Topoisomerases “are integral to gene expression, as they resolve DNA supercoiling that is generated during transcription.” Here is a video describing what that means and how fluoroquinolones work –

 


A 1999 study in Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis showed that fluoroquinolone antibiotics damage and destroy mitochondrial DNA. It makes sense that they would do so because mitochondria are the parts of our cells that are most closely related to bacteria.  Bacteria are destroyed by fluoroquinolone antibiotics through the unraveling of bacterial DNA and resulting apoptosis (programmed cell death). Sadly, mitochondria also suffer the same fate.

An article published in September, 2013 in Nature entitled “Topoisomerases facilitate transcription of long genes linked to autism” noted that topoisomerase inhibitors can adversely affect gene expression and, “topoisomerases facilitate the expression of a large number of ASD (Autism Spectrum Disorder) candidate genes, including many that are long and that are thought to have large effects on ASD pathology.” Basically, drugs that effect topoisomerases, chemotherapy drugs and fluoroquinolone antibiotics (which are chemotherapy drugs) can cause Autism genes to be expressed.

The article concludes by stating that:

“Our data suggest that chemicals or genetic mutations that impair topoisomerases, and possibly other components of the transcription elongation machinery that interface with topoisomerases, have the potential to profoundly affect the expression of long ASD candidate genes. Length-dependent impairment of gene transcription, particularly in neurons and during critical periods of brain development, may thus represent a unifying cause of pathology in in many individuals with ASD and other neurodevelopmental disorders.”

THIS IS HUGE. It is an environmental factor, topoisomerase inhibiting chemotherapy drugs including fluoroquinolone antibiotics, that cause the expression of Autism genes.

It should be noted that the specific drug studied in “Topoisomerases facilitate transcription of long genes linked to autism” is Topotecan, not fluoroquinolones. Topotecan is a topoisomerase I inhibitor whereas fluoroquinolone atibiotics are topoisomerase II (also known as DNA gyrase) and topoisomerase IV inhibitors. Further studies need to be done to definitively show whether or not fluoroquinolones have the same adverse effects as Topotecan.

HOWEVER, the Researchers note that:

TOP2 (topoisomerase II) enzymes, (particularly TOP2B) also participate in gene transcription. We next tested whether genetic or pharmacological inhibition of TOP2 enzymes could reduce the expression of long genes. Indeed, with new experiments and by re-analyzing data from others, we found that the TOP2A/TOP2B inhibitor ICRF-193 reduced gene expression in a length-dependent manner in cultured mouse cortical neurons, embryonic stem (ES) cells and ES-cell-derived neurons. There was extensive overlap between genes affected by ICRF-193 and topotecan in cortical neurons, particularly for long genes, and the magnitudes of these effects were highly correlated. Thus, TOP1 (topoisomerase I) and TOP2 (topoisomerase II) enzymes regulate the expression of many of the same genes.

This means that topoisomerase II inhibitors, also known as DNA gyrase inhibitors, such as fluoroquinolones do the SAME THING as the topoisomerase I inhibitors studied. Fluoroquinolone antibiotics – Cipro, Levaquin, Avelox and a few more – “profoundly affect the expression of long ASD candidate genes.”

26.9 MILLION prescriptions for fluoroquinolone antibiotics were given to people in 2011 alone. Quantities of prescriptions of these DNA altering drugs have been in the millions since their rise in popularity in the 1980s.

These popular antibiotics, prescribed for sinus infections, urinary tract infections, strep throat, traveler’s diarrhea, prostate infections, etc. ALTER DNA AND NEGATIVELY INFLUENCE GENE EXPRESSION (EPI-GENETICS) AND LEAD TO THE EXPRESSION OF AUTISM GENES. Genes. DNA. Epi-genetics. The bits of information that our cells pass from one generation to the next. The damaged DNA is passed from parent to child and from that child down to their children, and so on and so on.

Gene expression, epi-genetics, is tricky because so many factors influence how genes are expressed, and it is only recently that ways of measuring and describing epi-genetics have been discovered. Neil deGrasse Tyson is probably better at explaining epi-genetics than I am, so please check out this video –

 

One of the research scientists who Dr. deGrasse Tyson interviews notes that, “you’re not only what you eat, (you are) potentially what your mother ate and even what your grandparents ate” to show the power of the heritability of epi-genetic markers. Dr. deGrasse Tyson and the research scientist are discussing how food can effect epi-genetic markers and influence obesity throughout generations of mice. If food can effect epi-genetics that dramatically, just imagine how dramatically a drug that is intentionally designed to interfere with and unravel mitochondrial DNA can effect human heredity. Not only can a drug that a parent (not just mothers, the DNA of fathers contributes to 50% of everyone’s genes) took influence the epi-genetics of their child, but the epi-genetics of their grandchildren and great-grandchildren can be adversely effected as well.

So, children are inheriting damaged genes, the genes that control whether or not a person is Autistic, because their parent (or even grandparent – for future generations – fluoroquinolones haven’t been around long enough to mess up multiple generations of people – yet) took an ANTIBIOTIC that messed up their mitochondrial DNA. This is absurd. Generations of humans will continue to be plagued by high autism rates, possibly indefinitely, because a certain class of antibiotics that has dangerous and severe side-effects even to those who take them directly, has damaged their mitochondrial DNA. This entire horrifying situation is Bayer’s and Johnson & Johnson’s fault and they should be held accountable to humanity in every way possible.

Let me just back-pedal a little bit and say that many women who have been severely adversely effected by fluoroquinolone antibiotics have had healthy, happy, beautiful, smart babies. Many factors go into how genes are expressed. What you eat, music, positive thoughts and words, etc. can influence how your genes are expressed. If you have taken a fluoroquinolone antibiotic, you are not doomed to have an autistic child. But it really seems shameful, horrifying actually, to increase someone’s odds of having an autistic child by encouraging the expression of autism related genes synthetically, through an unneeded and destructive antibiotic, when other, safer, non-DNA-damaging antibiotics are available.

If I can figure out that fluoroquinolones have the same effects as Topotecan, and that damaged DNA and gene expression / epi-genetics markers can be passed on from generation to generation, with my Cipro frazzled brain, you can bet that Dr. Zylka and his team of undoubtedly brilliant Scientists also realize that topoisomerase II / DNA gyrase (and topoisomerase IV) inhibitors like fluoroquinolones are leading to the expression of autism genes. I thank these Scientists for what they have uncovered and published from the bottom of my heart, and I beg of them, please have enough courage and moral fortitude to stand up for what you know to be true – that fluoroquinolone antibiotics made by Bayer and Johnson & Johnson have severely, and possibly irreversibly, damaged the human gene pool in a way that is causing children, innocent children, to be hurt. Though there is little that can be done to stop the damage from being passed down through the generations, the people who have already been hurt by Bayer and J&J deserve compensation. The children who are living with Autism deserve compensation. Bayer and J&J hurt them, they hurt humanity, and they should pay for their sins. Without the word of Scientists to back up these assertions, no justice will ever come to the families. Dr. Zylka and others… please, do what’s right.

The Dangers of Fluoroquinolones Shouldn’t be a Surprise

This coalmine is littered with dead canaries. The Scientists who designed fluoroquinolones always knew that they were topoisomerase inhibitors that unraveled bacterial DNA. They may not have known that fluoroquinolones caused the expression of Autism related genes, that’s a recent discovery, but any claims not to know that these drugs are dangerous involves a huge amount of willful ignorance. In 1998 Stephen Fried published Bitter Pills: Inside the Hazardous World of Legal Drugs, describing his wife Diane’s severe adverse reaction to Floxin (a fluoroquinolone that is no longer popular, but is still available) that included severe CNS issues. Before and since publication of Bitter Pills, article after article, research paper after research paper has been published noting one danger of fluoroquinolones after another. Here is just a small sample of the information about the immediate dangers of fluoroquinolone antibiotics – http://floxiehope.com/links-resources/. So many people have been needlessly hurt by these drugs. Many of those who have been hurt have been screaming about their pain, trying to get people to listen, trying to save others from their sad fate – and their warnings have been unheeded. It is to be determined whether or not this article in Nature will change anything, whether or not people will pay attention to the canaries in the coalmine. I hope so. Regardless of whether or not the harm that has been done to human DNA is reversible, people deserve to know the truth. They deserve to know why autism rates have gone from 1 in 1,000 children in 1980 to 1 in 88 children in 2013. They deserve to be compensated for their losses. They deserve to be able to make appropriate and informed decisions regarding the drugs they take and, sadly, the reproduction choices they make.

Nalidixic Acid, the foundation of all quinolone and fluoroquinolone antibiotics was discovered in 1962 by George Lesher.  It took 51 years and indescribable damage to the human gene pool for the dangers of this DNA altering substance to be revealed.  May this be a lesson for all people intentionally altering the genes of humans, animals or plants.

Other Factors

Of course, there are some factors other than gene expression that contribute to Autism Spectrum Disorders. Sadly, many of those can also be explained by fluoroquinolone use. Direct application of fluoroquinolones (ear and eye drops that are fluoroquinolone based are commonly prescribed to children as young as 1 to treat their ear and eye infections, as opposed to the inherited exposure described above, has been shown to cause disruption of tubulin assembly, mitochondrial damage, and a cascade of interrelated brain and nervous system damage stemming from the ability of certain drugs and substances to inhibit deacetylation of histone.  All of these things have also been linked to Autism.

A Note About Vaccines

Studies have shown that, “certain individuals with a mild mitochondrial defect may be highly susceptible to mitochondrial specific toxins like the vaccine preservative thimerosal.”  Drugs that damage mitochondria, fluoroquinolones are not the only drugs that do so, combined with vaccines, can be toxic and can lead to a marked increase in oxidative stress, production of reactive oxygen species, cell death and possibly Autism Spectrum Disorders.

Adverse reactions to direct application of fluoroquinolones (again, as opposed to inherited exposure and direct application can come in the form of orally administered fluoroquinolones, ie pills, intravenously administered fluoroquinolones or topically administered fluoroquinolones, ie ear and eye drops) are often both delayed and triggered by exposure to another toxin. The 2008 lawsuit that got the Black Box Warning of tendon ruptures added to the warning label of orally and intravenously administered fluoroquinolones accepted drug reaction times of up to four months after the fluoroquinolone was taken as a reasonable time frame. Also, the warning labels for fluoroquinolones note that adverse reactions can occur several months after administration of the drug has stopped. Unfortunately, the evidence that I have for adverse reactions to fluoroquinolones being triggered by another toxin are anecdotal. However, I think that the anecdotes are illustrative. In my personal case, my adverse reaction to Cipro started a full two weeks after I had FINISHED taking the Cipro, when I started taking ibuprofen, a NSAID. Enough other people who are also suffering from fluoroquinolone toxicity also have reported adverse reactions to NSAIDs (and the warning label says, “Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies.” http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019537s082,020780s040lbl.pdf though I did not take NSAIDs in combination with the quinolone/fluoroquinolone nor have I suffered through convulsions – yet) for me to think that the ibuprofen triggered my severe adverse reaction. The CAUSE of my adverse reaction was the Cipro that I had taken two weeks earlier. The ibuprofen was simply the trigger. It would not have been dangerous on its own. However, since Cipro had started a cellular adverse reaction in my body, the ibuprofen became dangerous to me. (It should also be noted that my adverse reaction began when I started my period and that hormones may be related to fluoroquinolone toxicity as well – again, sorry for the anecdotally based assertion.) It should be explored whether or not vaccines can TRIGGER adverse reactions to other drugs – especially drugs that damage mitochondria. If this is the case, the earlier administered drugs are the cause of the problem and the vaccines are simply the trigger – but they’re not exactly innocent either. All of these assertions should be explored further than I have the resources or expertise to do.

Tragedy

As someone who has personally been severely adversely effected by a fluoroquinolone antibiotic, Cipro, which caused central, peripheral and autonomic nervous system problems as well as damage to the connective tissue throughout my body, I always suspected that the dangerous and tragic effects of fluoroquinolones were going to explode into common consciousness at some point. I hoped that it would blow up because of advocacy efforts and that it wouldn’t require a tragedy for the screams of the victims of fluoroquinolones to be noticed. I suspected that my hope was ill-founded though. I thought that a difficult to treat major infection would make its rounds and that everyone would take a fluoroquinolone – and that a large number of people would get sick so that it became undeniable what these drugs did. I imagined a scenario where a foreign leader got sick from a fluoroquinolone and had a fit over it – causing an international relations snafu. Though either of these scenarios would have involved a huge amount of sadness for the victims, they also would have involved some vindication and righteousness on my part over the fact that I KNEW and I tried to warn everyone. Not in my wildest dreams did I imagine that the tragedy caused by fluoroquinolones would be a slow-moving one and that it had been happening over my lifetime. Never would I have imagined that something as insidious and tragic as Autism was the tragedy caused by fluoroquinolones and that one in eighty-eight children would be effected. Never would I have imagined that our DNA would be so profoundly affected by these dangerous drugs that even if everything that I wished for – that their use be severely restricted and that victims of these drugs be compensated – came true, that the havoc that these drugs caused would not be stopped. I am profoundly and deeply saddened by this situation. I cannot express how much my soul aches over the fact that the victims of these drugs are children, the innocent among us, those who need our protection, the babies. They have been let down. Humanity has been let down and I cannot quit sobbing for all of our souls.

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